A Vertebral Compression Fracture (VCF) occurs when a spinal vertebra collapses. which can lead to severe pain and deformity. It is the most common fracture in patients with osteoporosis.

The minimally invasive procedures for treating VCFs today include vertebroplasty and kyphoplasty. In these procedures, bone cement is injected through a hollow needle into the fractured vertebra to stabilize and strengthen the vertebra.

Bone cement consists of a liquid monomer and a copolymer powder, which are mixed together in the operating room. The liquid mixture begins to harden immediately. This leaves the surgeon only a few minutes to safely and accurately inject the liquid cement before it hardens inside the fractured vertebra.

The liquid cement may leak out of the vertebra, which can lead to fractures in adjacent vertebrae, pulmonary emboli, or spinal cord damage.


SetBone Medical introduces a new generation of bone cement that seeks to provide a safer and more efficient treatment.

SetBone’s ready-to-use, bone filler devices are pre-filled with SetBone’s proprietary cement. There’s no need for mixing or other on-site preparations. 

Using the same surgical approach, SetBone's cement is injected in its amorphous solid state, eliminating the risk of leakage.


The SetBone cement maintains a constant viscosity state and gives the surgeon unlimited working time. SetBone's cement hardens only when exposed to body temperature.


  • High viscosity
    reduces risk of leakage

  • Ready-to-use
    no need for on-site preparation

  • Cures only when exposed to body temperature
    unlimited working time; surgeon can work safely and achieve proper vertebral filling


  • Low exothermic reaction
    no polymerization heat; no damage to tissue


  • Same surgical approach
    same procedure, same tools

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